State Medical Boards (SMBs) can take severe disciplinary actions (e.g., license revocation or suspension) against physicians who commit egregious wrongdoing in order to protect the public. However, there is noteworthy variability in the extent to which SMBs impose severe disciplinary action. In this manuscript, we present and synthesize a subset of 11 recommendations based on findings from our team’s larger consensus-building project that identified a list of 56 policies and legal provisions SMBs can use to better protect patients from egregious (...) wrongdoing by physicians. (shrink)

We report the identification of a recurrent, 520-kb 16p12.1 microdeletion associated with childhood developmental delay. The microdeletion was detected in 20 of 11,873 cases compared with 2 of 8,540 controls and replicated in a second series of 22 of 9,254 cases compared with 6 of 6,299 controls. Most deletions were inherited, with carrier parents likely to manifest neuropsychiatric phenotypes compared to non-carrier parents. Probands were more likely to carry an additional large copy-number variant when compared to matched controls. The clinical (...) features of individuals with two mutations were distinct from and/or more severe than those of individuals carrying only the co-occurring mutation. Our data support a two-hit model in which the 16p12.1 microdeletion both predisposes to neuropsychiatric phenotypes as a single event and exacerbates neurodevelopmental phenotypes in association with other large deletions or duplications. Analysis of other microdeletions with variable expressivity indicates that this two-hit model might be more generally applicable to neuropsychiatric disease. © 2010 Nature America, Inc. All rights reserved. (shrink)

The extant marketing literature provides little guidance for theory development or practice with regard to questions of ethical conformity and the resulting market response. To begin to bridge this research gap, we advance a theoretical framework of ethical conformity in marketing, appealing to marketing ethics, management strategy, and sociological foundations. We set the stage for our theoretical arguments by considering the role of normative expectations related to marketing practices and behaviors held by societal constituents. Against this backdrop, we propose drivers (...) of conformity in marketing, including practices consistent with both overconformity and underconformity. The framework allows us to advance testable research propositions by which questions of ethical conformity may be explored. We conclude by suggesting additional future research needed to develop the domain, specifically in the form of empirical inquiries uncovering firm strategic decisions with ethical implications. (shrink)

The antisaccade task provides a model paradigm that sets the inhibition of a reflexively driven behaviour against the volitional control of a goal-directed behaviour. The stability and adaptability of antisaccade performance was investigated in 23 neurologically healthy individuals. Behaviour and brain function were measured using functional magnetic resonance imaging (fMRI) prior to and immediately following two weeks of daily antisaccade training. Participants performed antisaccade trials faster with no change in directional error rate following two weeks of training; however this increased (...) speed came at the cost of the spatial accuracy of the saccade (gain) which became more hypometric following training. Training on the antisaccade task resulted in increases in fMRI activity in the fronto-basal ganglia-parietal-cerebellar ocular motor network. Following training, antisaccade latency was positively associated with fMRI activity in the frontal and supplementary eye fields, anterior cingulate and intraparietal sulcus; antisaccade gain was negatively associated with fMRI activity in supplementary eye fields, anterior cingulate, intraparietal sulcus and cerebellar vermis. In sum, the results suggest that following training, larger antisaccade latency is associated with larger activity in fronto-parietal-cerebellar ocular motor regions, and smaller antisaccade gain is associated with larger activity in fronto-parietal ocular motor regions. (shrink)

Abstract A number of recent studies suggest that income and social inequality (as opposed to poverty itself) have detrimental consequences on people's health. These studies argue that while the poor may suffer the most from inequality, the rich also suffer. On closer inspection, however, it emerges that the basic arguments and evidence that inequality has a causal effect on health are wanting in many respects.

The article retraces three important steps along the path of Derrida’s Heidegger interpretation in The Beast and the Sovereign, Volume II. Readings of The Fundamental Concepts of Metaphysics, Introduction to Metaphysics, and “The Onto-Theo-Logical Constitution of Metaphysics” complement and further develop Derrida’s deconstruction of Heidegger, which revolves around the term “Walten” and its role in the world-formation that makes community possible. The analysis of what Derrida calls the hyper-sovereignty of Walten reveals an ethico-political ambiguity in Heidegger’s texts. On the one (...) hand, this hyper-sovereignty registers as a super-sovereign violence that founds theological-political world-constructs through the exclusion of those deemed other. On the other hand, like différance it serves as the condition of impossibility of a common world. Following Derrida’s provocation, I develop this second sense to argue that the dissolution of the common world entails an ethical imperative to carry the other with whom one has nothing in common. (shrink)

:Our theoretical claim is that racism was consciously devised, and later evolved, to serve two conflicting purposes. First, racism served a legal-economic purpose, legitimating ownership and savage treatment of slaves by southern whites, preserving the value of property rights in labor. Second, racism allowed slave owners to justify, to themselves and to outsiders, how a morally "good" person could own slaves. Racism portrayed African slaves as being less than human, or else as being other than human. The interest of the (...) historical narrative presented here is the emergence of racial chattel slavery as a coherent and fiercely defended ideal, rather than the "necessary evil" that had been the perspective of the Founders. The reason that this is important is that the ideology of racism persisted far beyond the destruction of the institution of slavery, through Reconstruction, Jim Crow, and in some ways persisting even today. This work is an example of the problems of assuming that there is a "feedback" mechanism by which moral intuitions are updated and perfected; to the contrary, as suggested by Douglass North, even socially inferior ideologies can prove extremely persistent. (shrink)

In recent years, historians have rediscovered the religious dimensions of the Enlightenment. This volume offers a thorough reappraisal of the so-called “Catholic Enlightenment” as a transnational Enlightenment movement. This Catholic Enlightenment was at once ultramontane and conciliarist, sometimes moderate but often surprisingly radical, with participants active throughout Europe in universities, seminaries, salons, and the periodical press._ In _Enlightenment and Catholicism in Europe: A Transnational History_, the contributors, primarily European scholars, provide intellectual biographies of twenty Catholic Enlightenment figures across eighteenth-century Europe, (...) many of them little known in English-language scholarship on the Enlightenment and pre-revolutionary eras. These figures represent not only familiar French intellectuals of the Catholic Enlightenment but also Iberian, Italian, English, Polish, and German thinkers. The essays focus on the intellectual and cultural factors influencing the lives and works of their subjects, revealing the often global networks of intellectual sociability and reading that united them both to the Catholic Enlightenment and to eighteenth-century policies and projects. The volume, whose purpose is to advance the understanding of a transnational "Catholic Enlightenment," will be a reliable reference for historians, theologians, and scholars working in religious studies. "This is a compelling collection on an important subject. Its transnational and biographical approach helps one to see eighteenth-century Catholicism and the Enlightenment itself in fresh and interesting ways." — Darrin M. McMahon, Florida State University_. (shrink)

In 1773, Pope Clement XIV suppressed the Society of Jesus, a dramatic, puzzling act that had a profound impact. This volume traces the causes of the attack on the Jesuits, the national expulsions that preceded universal suppression, and the consequences of these extraordinary developments. The Suppression occurred at a unique historical juncture, at the high-water mark of the Enlightenment and on the cusp of global imperial crises and the Age of Revolution. After more than two centuries, answers to how and (...) why it took place remain unclear. A diverse selection of essays - covering France, Spain, Portugal, Italy, the Netherlands, China, Eastern Europe, and the Americas - reflects the complex international elements of the Jesuit Suppression. The contributors shed new light on its significance by drawing on the latest research. Essential reading on a crucial yet previously neglected topic, this collection will interest scholars of eighteenth-century religious, intellectual, cultural, and political history. (shrink)

Does nostalgia for one’s time at university predict current intentions to engage with the university? In Study 1, United States participants’ nostalgia for their university experience (university nostalgia) at a southern public university predicted stronger intentions to socialize with fellow alumni, attend a future reunion, volunteer for their university, and donate money to their university. Study 2 replicated these findings with alumni from a northeastern private university, and extended them by finding that the links between university nostalgia and university engagement (...) emerged even when controlling for the positivity of university experience. In both studies, feelings of university belonging mediated most of the associations between university nostalgia and university engagement. In Study 2, the positivity of the university experience moderated the relation between university nostalgia and two indices of university engagement. Specifically, university nostalgia was more strongly associated with intentions to attend a reunion and donate money among those who had a relatively negative university experience. Nostalgia for one’s university past predicts future engagement with the university as well as its members. (shrink)

This paper offers a deconstructive reading of the pure actuality of the un­moved mover of Aristotle’s Metaphysics Lambda. Aristotle describes this first, unmoved principle of movement as a divine sovereign—the king of the cosmos—and maintains that the good governance of the cosmos depends on its unmitigated unity and pure actuality. It is striking, then, when Giorgio Agamben claims that Aristotle bequeathed the paradigm of sovereignty to Western philosophy not through his arguments for the pure actuality of the unmoved mover but (...) rather through his description of the essence of potentiality. An interpretation of Aristotle’s account of potentiality in Metaphysics Theta therefore prepares the way for a deconstruction of the unity and pure actuality of the divine sovereign. I argue that the repetition of nous in Aristotle’s description of the divine thinking of thinking betrays traces of division and difference at the heart of divine sovereignty. If this is the case, then actuality and potentiality become indis­cernible at the level of the absolute and the sovereign corresponds to the bifurcated site of this indiscernibility. (shrink)

This essay explores the historical roots of biopolitics by investigating the structural homology between the supremely virtuous king discussed in Aristotle’s Politics and the sovereign living law advanced in On Law and Justice, accepted here as authored by Archytas of Tarentum. Archytas’s sovereign incarnates a divine law in order to ground the written law of the city and to constitute the way of life proper to the citizenry. The identity of life and law in his person exempts this sovereign from (...) the written laws he grounds just as Aristotle’s king cannot be subjected to law because he is a law unto himself. Despite this homology, Archytas’s sovereign exemplifies a highly determinate way of life fully constituted by law while an analysis of Aristotle’s king reveals a double determination of the virtuous exemplar as both sovereign and exile. This double determination both exhibits and complicates the logic of exclusion that, for Agamben, makes Western politics biopolitical from its inception. (shrink)

The nature–nurture controversy has been with us since it was first outlined by Plato and Aristotle. Nobody likes it anymore. All reasonable scholars today agree that genes and environment interact to determine complex cognitive outcomes. So why does the controversy persist? First, it persists because it has practical implications that cannot be postponed (i.e., what can we do to avoid bad outcomes and insure better ones?), a state of emergency that sometimes tempts scholars to stake out claims they cannot defend. (...) Second, the controversy persists because we lack a precise, testable theory of the process by which genes and the environment interact. In the absence of a better theory, innateness is often confused with (1) domain specificity (outcome X is so peculiar that it must be innate), (2) species specificity (we are the only species who do X, so X must lie in the human genome), (3) localization (outcome X is mediated by a particular part of the brain, so X must be innate), and (4) learnability (we cannot figure out how X could be learned, so X must be innate). We believe that an explicit, plausible theory of interaction is now around the corner, and that many of the classic maneuvers to defend or attack innateness will soon disappear. In the interim, some serious errors can be avoided if we keep these confounded issues apart. That is the major goal of this chapter: not to attack innateness but to clarify what claims about innateness are (and are not) about. (shrink)

This article describes an adjacency-pair organized course of action in the institutional context of customers calling an electronics repair facility to request the status of equipment they have previously sent in for repair. Relative to the majority of adjacency-pair sequences described in previous research, this course of action is rare in that it is essentially composed of three turns, including status solicitation, status response, and acceptance/rejection of status response. After defending this finding, we situate and discuss its significance relative to (...) prior research – in both ordinary and institutional contexts – on adjacency-pair sequence organization, including implications for sequence-based relevance rules, such as preference organization. Finally, we outline a possible general explanation for why some initiating actions set in motion essentially three-turn courses of action, and offer a candidate example in ordinary conversation. (shrink)

This study examines firms that have experienced an industrial and/or environ-mental crisis and proposes that top management team (TMT) characteristics will affect a firm's ability to minimize the severity of these crisis events. Specifically, heterogeneity in the TMT will exhibit a curvilinear (U-shaped) relationship with the severity of firm crises. Our results suggest that a moderate level of age and tenure heterogeneity are positively related to a firm's ability to successfully minimize the severity of crises. Variance in educational backgrounds was (...) unrelated to crisis severity. Functional background heterogeneity exhibited a curvilinear relationship with crisis severity but was not U-shaped as hypothesized. (shrink)

The most common form of the CO2‐fixing enzyme rubisco is a form I enzyme, heretofore found universally in oxygenic phototrophs (cyanobacteria and plastids) and widely in proteobacteria. Two groups(1–4), however, now report that in dinoflagellate plastids the usual form I rubisco has been replaced by the distantly related form II enzyme, known previously only from anaerobic proteobacteria. This raises the important question of how such an oxygensensitive rubisco could function in an aerobic organism. Moreover, the dinoflagellate rubisco has unusual molecular (...) properties: it is encoded as a polyprotein, by nuclear (rather than plastid) genes, and these genes contain noncanonical spliceosomal introns. The nuclear location and alphaproteobacterial affinity of dinoflagellate rubisco genes hint at a possible mitochondrial origin and highlight the extraordinary richness of lateral gene transfers, both between and within organisms, that have occurred during rubisco evolution. (shrink)

The small, relatively constant size and conservative evolution of chloroplast DNA (cpDNA) make it an ideal molecule for tracing the evolutionary history of plant species. At lower taxonomic levels, cpDNA variation is easily and conveniently assayed by comparing restriction patterns and maps, while at higher taxonomic levels, DNA sequencing and inversion analysis are the methods of choice for comparing chloroplast genomes. The study of cpDNA variation has already yielded important new insights into the origin and evolution of many agriculturally important (...) crop plants, and promises to significantly enhance our phylogenetic understanding of the major lines of descent among land plants and algae. (shrink)

This collection of ten original essays was first published in 1977. It engages the 'crisis in sociology' at the most fundamental level of thought and experience. Existential sociology is defined as the study and understanding of all forms of human existence. Without seeking to erect a pristine philosophical sanctuary of its own, Existential Sociology examines and criticizes the underlying philosophical assumptions of previous theories of social science, while elaborating its own approach to human understanding. The contributors are concerned with constructing (...) practical as well as theoretical truths about social life - how we feel, think and act. In contrast to most other sociologies, the emphasis is on the independence and dominance of human feelings over the evaluative and cognitive features of social actions. Students and teachers of sociology and people in related fields interested in the connection between social science and their own subjects will find Existential Sociology useful and absorbing. (shrink)

ABSTRACT:Despite widespread attention to corruption and organizational change in the literature, to our knowledge, no research has attempted to understand the linkages between these two powerful organizational phenomena. Accordingly, we draw on major theories in ethics, sociology, and management to develop a theoretical framework for understanding how organizational change can sometimes generate corruption. We extend anomie theory and ethical climate theory to articulate the deinstitutionalization of the normative control system and argue that, through this deinstitutionalization, organizations have the potential to (...) become incubators for corruption. We qualify this process by proposing conditions more ripe for anomie and under which this deinstitutionalization is more likely to occur, propounding moderating relationships that influence organizational reconfiguration. Examples of turbulence in the contemporary business environment that can trigger change highlight our discussion. We conclude with managerial implications, offering means by which the deleterious effects of corruption may be arrested or controlled. (shrink)

This article considers the methodology of entangled history and its potential for nuancing or circumventing scholarly controversies over the nature and extent of the Enlightenment in eighteenth-century religious thought. After sketching the development of entangled history theory and its potential applicability to studying the Enlightenment, the rest of the article provides a case study of one way in which the insights discussed in the first parts of the article can be applied to current controversies about how historians construct the concept (...) of Enlightenment. As will be shown, the transdiscursive entanglement of Jesuit missionary output with the debates between Voltaire and Bergier illustrates the mutability and rhetorical malleability of historical paradigms concerning the Enlightenment and religion. (shrink)

The Benedictine Dom Léger-Marie Deschamps and the philosophical Abbé Claude Yvon may indeed be minor eighteenth-century figures, and they both may be considered to have emerged from the Catholic side of something Helena Rosenblatt has dubbed the Christian Enlightenment, but neither of these figures is neatly “conservative” (as Mark Curran defines it), nor are they fully “radical” (in the sense of having contributed to the Radical Enlightenment). Rather, Deschamps and Yvon are among a number of eighteenth-century figures who do not (...) fit neatly into the expected parameters of Catholic, Christian, Religious or Radical Enlightenment. This article argues that the entanglement of both heterodoxy and orthodoxy, and of sociopolitical progressivism and conservatism, is characteristic of Yvon’s and Deschamps’s particular engagement with what Vincenzo Ferrone describes as the cultural revolution of the eighteenth century. This study of these under-examined Catholic scholars further suggests that conventional and tidy scholarly narratives of the history of Enlightenment should be further problematized. (shrink)

Concussion in sports is a topic that is receiving increasing amounts of publicity and attention. Increasing recognition of concussion as well as improving understanding of the short- and long-term physiologic effects of concussion have resulted in widespread legislation governing the recognition and treatment of sports concussion. The increasing amount of medical research in the field and oftentimes subjective symptoms of concussion leave many ethical questions to be answered.

Emerging research shows a strong connection between brain areas governing cognition and motor behavior. Yet, research investigating the negative aftereffects of cognitive control exertion on task performance has not considered the potential role of areas governing motor behavior. The present study investigated the effects of high cognitive control exertion on task self-efficacy and exercise performance in children. A secondary purpose was to investigate whether motor coordination influences the change in exercise performance differently following low versus high cognitive control exertion. Participants (...) (N = 70) performed two isometric handgrip endurance trials separated by a Stroop task, which was either congruent (low cognitive control) or incongruent (high cognitive control). Motor coordination was assessed prior to the first endurance trial. Task self-efficacy for performing the second endurance trial was assessed following the Stroop task. Participants in the high cognitive control condition reported lower task self-efficacy and showed a reduction in endurance exercise performance. Task self-efficacy mediated the cognitive control – performance relationship. Participants scoring lower on motor coordination showed the greatest declines in exercise performance following high cognitive control, whereas motor coordination did not affect performance following low cognitive control. The results of this study provide evidence that task self-efficacy and exercise performance are also negatively affected in children following high cognitive control, and interestingly, these effects are exacerbated among those scoring lower in motor coordination. We recommend future research investigate motor coordination as a potential mechanism for the reductions in both cognitive and physical task performance following the prolonged exertion of high cognitive control. (shrink)

The Consensus Statement of the Third International Congress on Concussion in Sport in November 2008 defined concussion as a “complex pathophysiologic process affecting the brain, induced by traumatic biochemical forces.” Definitions of concussion vary slightly between various professional organizations of neurosurgeons, neurologists, and orthopedic surgeons, but all share the common characteristics of trauma affecting the head or body resulting in transient neurologic deficits or symptoms. Underlying the symptoms of concussion is a complex pathophysiologic process at the cellular level. While concussion (...) is typically thought of as resulting from a direct impact to the head, a concussion can also be sustained as a result of an impact to the body causing the force of the impact to be transmitted to and absorbed by the brain. (shrink)